The Different Levels of Bioprocess Software: How They Address Specific User Requirements and Finding the Right One for You
(PresseBox) - Providing a single software solution to suit the full range and diversity of all biological cultivations would be an impossible task. A universal solution would be over-specified and expensive for most users, whilst similarly, a basic solution may not provide enough capabilities to suit all needs. This overview explores different user requirements and their best choice of bioprocess software.
1. Levels of a Bioprocess Software
By its nature, bioprocess software is multi-layered. Different categories of users have layers in terms of the features they need from bioprocess software:
Those users with the basic needs may only require the software features integrated into the bioreactor
Most users will require the extra capability provided by external bioprocess software
Some advanced users may need specific features beyond the standard software package, such as process validation via advanced user management and additinal security features.
2. How do You Know Which level to opt for and Why?
Each choice of bioprocess software level will have its own license and related costs.t software levels can be compared to your list in an objective way. Other stakeholder?s opinions, budget, timing and futureproofing will also play a part in the decision-making process.
The user categories will now be explored in more detail to provide a better idea of how to get the most from each software level. This will help you decide on initial choices if and when to upgrade and to which level. For many users, the decision will be made by the application and process itself.
3. User types
3.1 Basic User
A basic user has no perceived need for specialised biprocess software.
Basic requirements include:
Output of process values plus set points and controller status
Display real-time data as text and/or charts
Start and stop batches
Log data for a limited timeframe and archive to external memory
Display alarms and archive to external memory
Export data t in Comma Separated Value or Excel file formats
Store used setting and/or recipe files
3.2 Standard User
This group can be best described as thise whose needs are met by the standard features provided. The fact that many popular features are included in a ?standard version? is the reason why it is a clear leader in numeric terms. Although, it is likely that an upgrade will be necessary in the future.
A typical standard user would need the basics plus some combination of the following:
Analysis values (including addition of data post-archive)
Comparison of real-time and archived batches
Export of data over a network
Printing of charts
Connection of peripherals
Calculated values
Time-based control in phases
Simple cascades
Feeding in different steps
Pump timings recorded
Store control sequence files
Multi-vessel logging/control
Connection to third-party devices for mixed installations
3.3 Advanced
This category equates to full SCADA software plus advanced features related to
Offers customisation possibilities
Multiple set up of batches simultaneously
Full reporting with the output of alarms, recipes, soft sensors and workflows.
Data supplied in real time to other laboratory software packages
Full documentation provided for validation, QC and scale-up purposes
Integration with other software for specific purposes e.g. modelling in Matlab.
Central location for data and meta-data including libraries for organisms, culture media and recipes.
Multi-group planning capabilities
This is aimed at users with a product as an end goal. Data generated in the laboratory will need to be shared for scale-up and may count towards a submission for a product license. The units connected would be the actual production vessels.
This is usually the domain of industrial users and may tie together research, scale-up and production facilities. which could be included in this group are
Multi-user with a mix of HMI and software for peripherals to be integrated
May also be multi-user and may be multi-site
Numbers of real-time links in the high tens of units
Well-specified server(s) needed
For use
Summary
This article has explored different layers of bioprocess software how they can be mapped
A basic user may be able to manage his bioprocess with a local HMI controller and may not require external software, although they would miss out on advanced automation, archiving and data analysis.
A standard user should be well served by a standard software package by using what is needed for their application and ignoring the rest. This will suit most users, but in order to progress, a future upgrade may be required.
An advanced user package equates to the needs of process validation and working across several groups. The concept of the process is a big element, with many elements defined and stored in libraries within the bioprocess software.
The super-user is a rarest category, involving large projects and customized approach. Multi-group and multi-site operation are the key. As tens of bioreactors may be connected at one time, security and reliability are paramount.
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Datum: 03.08.2020 - 05:20 Uhr
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