VITROCELL® Cloud Alpha 96
96-well Air/Liquid Interface (ALI) exposure / For reliable high throughput testing of cell cultures
(PresseBox) - The VITROCELLnality enables fully automated processes with an all-in-one control unit. Everyday experiments at the air/liquid interface have never been easier.
The new Cloud Alpha 96 series was developed as a result of numerous customer requests and is now capable to expose mammalian cell cultures in Corning
Exposure at the Air / Liquid Interface
In response to the scientific need to expose in physiologically relevant conditions, the VITROCELLances with the culture media.
Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are received directly. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.
Two Versions available
The system is available as Cloud Alpha 96 and Cloud Alpha 96 +. The latter features an integrated Quartz Crystal Microbalance for online assessment of the deposited mass.
Dosimetry using Quartz Crystal Microbalance (QCM)
The QCM sensor is integrated in the Cloud Alpha 96 + exposure module. It is capable of measuring the deposited mass at a resolution of 10 nanogram/cm2 per second. Results are reported online by the VITROCELL
Choice of three types of nebulizers
The system comes with a choice of 3 types of vibrating mesh nebulizers having droplet MMAD ranges of 2.5 ? 6.0 ?m, 2.5 ? 4.0 ?m and 4.0 ? 6.0 ?m.
Recommended nebulisation volumes are 200 ?l (Cloud Alpha 96) and 300 ?l (Cloud Alpha 96 +). So the device is particularly suitable for testing whenever small quantitities of testing materials are available.
Key Features:
Integrated controller for aerosol generator
Optional integrated microbalance controller
Defined experiment recipes
Automatisation of the experiment by nebulization time or by user-defined volume
Output rate database for nebulizers
Heating system
Optional PowerVent function: evacuation of potentially residual aerosols via vacuum pump
Designed for screening of inhaled drugs, toxicity testing of inhaled substances such as chemicals or nanoparticles and virus research
Advanced in vitro exposure systems
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Advanced in vitro exposure systems
Datum: 24.08.2020 - 09:34 Uhr
Sprache: Deutsch
News-ID 1560293
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