VITROCELL® Cloud Alpha 96

96-well Air/Liquid Interface (ALI) exposure / For reliable high throughput testing of cell cultures

ID: 1560293
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(PresseBox) - The VITROCELLnality enables fully automated processes with an all-in-one control unit. Everyday experiments at the air/liquid interface have never been easier.

The new Cloud Alpha 96 series was developed as a result of numerous customer requests and is now capable to expose mammalian cell cultures in Corning

Exposure at the Air / Liquid Interface

In response to the scientific need to expose in physiologically relevant conditions, the VITROCELLances with the culture media.

Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are received directly. This approach allows for more credible and authentic results than by submerged exposure due to a closer replication of the human physiology.

Two Versions available

The system is available as Cloud Alpha 96 and Cloud Alpha 96 +. The latter features an integrated Quartz Crystal Microbalance for online assessment of the deposited mass.

Dosimetry using Quartz Crystal Microbalance (QCM)

The QCM sensor is integrated in the Cloud Alpha 96 + exposure module. It is capable of measuring the deposited mass at a resolution of 10 nanogram/cm2 per second. Results are reported online by the VITROCELL

Choice of three types of nebulizers

The system comes with a choice of 3 types of vibrating mesh nebulizers having droplet MMAD ranges of 2.5 ? 6.0 ?m, 2.5 ? 4.0 ?m and 4.0 ? 6.0 ?m.

Recommended nebulisation volumes are 200 ?l (Cloud Alpha 96) and 300 ?l (Cloud Alpha 96 +). So the device is particularly suitable for testing whenever small quantitities of testing materials are available.

Key Features:

Integrated controller for aerosol generator

Optional integrated microbalance controller

Defined experiment recipes

Automatisation of the experiment by nebulization time or by user-defined volume

Output rate database for nebulizers



Heating system

Optional PowerVent function: evacuation of potentially residual aerosols via vacuum pump

Designed for screening of inhaled drugs, toxicity testing of inhaled substances such as chemicals or nanoparticles and virus research

Advanced in vitro exposure systems



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Date: 08/24/2020 - 09:34
Language: English
News-ID 1560293
Character count: 2066
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Firma: VITROCELL Systems GmbH
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Stadt: Waldkirch
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