Information Update/Proton Pump Inhibitors: Risk of Bone Fractures
(firmenpresse) - OTTAWA, ONTARIO -- (Marketwired) -- 04/04/13 -- Health Canada is informing Canadians and Canadian health care professionals of the potential risk of bone fractures associated with the use of drugs known as proton pump inhibitors.
Proton pump inhibitors (PPIs) are drugs used to reduce stomach acid and are widely used to treat conditions such as acid reflux (heartburn) and stomach ulcers.
Several scientific studies suggest that PPI therapy may be associated with a small increased risk for fractures of the hip, wrist, or spine related to osteoporosis, a disease resulting in the weakening of bones. The risk of fracture was higher in patients who received multiple daily doses of PPIs and therapy for a year or longer. Additional risk factors for osteoporosis, such as age, gender and the presence of other health conditions, may also contribute to the increased risk of fractures.
At Health Canada's request, manufacturers of all PPIs marketed in Canada have updated the drug labels for their products to include information on this risk.
Healthcare professionals should closely monitor patients with risk factors for osteoporosis who use PPIs, and report any adverse reactions to Health Canada.
Health professionals are also reminded that PPIs should be prescribed at the lowest dose and shortest duration of therapy appropriate to the condition being treated.
What patients should do
If you are taking PPIs and are at risk of osteoporosis, or are unsure of whether you are at risk, please consult your healthcare professional.
Health Canada has previously communicated with consumers and healthcare professionals regarding , and potential interactions between PPIs and and .
Drug labels, also known as "Product Monographs", contain important prescribing and safety information for health professionals and patients, and are available by search of Health Canada's .
Report a health or safety concern
- Call toll-free at 1-866-234-2345
- Visit Health Canada's Web page on for information on how to report online, by mail or by fax
Proton Pump Inhibitors drugs currently marketed in Canada
The following proton pump inhibitors are available in Canada:
PPIs are also available in combination with other drugs, for example: Vimovo (contains esomeprazole).
Stay connected with Health Canada and receive the latest advisories and product recalls using tools.
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Contacts:
Media Inquiries:
Health Canada
613-957-2983
Public Inquiries:
613-957-2991
1-866-225-0709
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Datum: 04.04.2013 - 13:00 Uhr
Sprache: Deutsch
News-ID 1213571
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