Cynapsus Therapeutics Inc. : Cynapsus Therapeutics appoints Dr. Abraham Lieberman to Clinical Advisory Board
(Thomson Reuters ONE) -
April 23, 2012
TORONTO, CANADA - Cynapsus Therapeutics, a specialty pharmaceutical company
developing an improved dosing formulation of an approved drug used to treat the
symptoms of Parkinson's disease, today announced that it has appointed Dr.
Abraham Lieberman to its Clinical Advisory Board (CAB). Dr. Lieberman is the
Director of the Muhammad Ali Parkinson Center and Movement Disorder Clinic of
the Barrow Neurological Institute at St. Joseph's Hospital and Medical Center.
The news follows completion of the Company's first human clinical study of APL-
130277, a reformulation of an approved drug (Apomorphine), for the treatment of
motor fluctuation in Parkinson's disease. The new appointment enhances the
range and depth of expertise of the CAB, which provides medical, clinical and
strategic guidance for the Company's product development and commercialization
activities.
"Cynapsus is very pleased to have Dr. Lieberman join our Clinical Advisory
Board. His vast knowledge and commitment to improving treatments and outcomes
for Parkinson's patients will be especially valuable as we advance APL -130277
towards clinical practice," said Anthony Giovinazzo, President and Chief
Executive Officer of Cynapsus. "Dr. Lieberman joins an international group of
Clinical Advisory Board members, including Dr. Warren Olanow and Dr. Fabrizio
Stocchi. Collectively their experience in clinical trial design and their track
record for advancing the care of patients with Parkinson's disease is
unparalleled. We are fortunate to have their support."
About Dr. Abraham Lieberman
Dr. Lieberman, M.D., is the Director of the Muhammad Ali Parkinson Center and
the Movement Disorder Clinic of Barrow Neurological Institute at St. Joseph's
Hospital and Medical Center. Dr. Lieberman earned an AB degree at Cornell
University, in Ithaca, New York, and a medical degree at the New York University
(NYU) School of Medicine in New York. He is board certified in neurology and
psychiatry, and is a fellow of the American Academy of Neurology and the
American Neurological Association, and a member of the Movement Disorder
Society. Dr. Lieberman is the principal or co-principal investigator of more
than 200 studies on such topics as the mechanism of action of levodopa; the
early and late use of dopamine agonists; the diagnosis and treatment of anxiety,
depression, and dementia in Parkinson's disease; and the treatment of fainting,
drooling, difficulty breathing, and swallowing in Parkinson's disease. Dr.
Lieberman has written six Parkinson's disease books including "100 Questions and
Answers about Parkinson's Disease," which is the largest selling book on the
disease.
About Dr. Warren Olanow
Warren Olanow, M.D. is the Henry P. and Georgette Goldschmidt Professor and
Chairman of the Department of Neurology at the Mount Sinai School of Medicine in
New York City and Chief of the Neurology Service at the Mount Sinai Hospital. He
received his medical degree from the University of Toronto, performed his
neurology training at the New York Neurological Institute at Columbia
University, and did post-graduate studies in neuroanatomy at Columbia
University. He served on the faculties of McGill University, Duke University,
and the University of South Florida prior to assuming his present position. Dr.
Olanow has authored more than 300 publications primarily related to Parkinson's
disease and neurodegeneration. He is currently President of the Movement
Disorder Society and Treasurer of the American Neurological Association.
About Dr. Fabrizio Stocchi
Fabrizio Stocchi M.D., PhD, is a Professor of Neurology and Director of the
Parkinson's disease and Movement Disorders Research Centre at the Institute for
Research and Medical Care, IRCCS San Raffaele, Rome, Italy. He is also a
Scientific Advisor of the Institute for Parkinson's disease Research in Vicenza.
Professor Stocchi was awarded his MD from the University of L'Aquila and his PhD
from the University of Catania. Professor Stocchi's research activities have
centered on neuropharmacology in the field of movement disorders and
neurodegenerative diseases. He has published many books and papers on the
genetics, clinical diagnosis, characterization and treatment of Parkinson's
disease, as well as in preclinical research into the disease. He is an active
member of 11 societies, including the Movement Disorder Society, the European
Clinical Neuropharmacology Society and the European Federation Neurological
Society.
About Cynapsus Therapeutics
Cynapsus is a specialty pharmaceutical company developing an improved dosing
formulation of an approved drug used to treat the symptoms of Parkinson's
disease. Over one million people in the United States and an estimated 5 million
people globally suffer from Parkinson's disease. Parkinson's disease is a
chronic and progressive neurodegenerative disease that impacts motor activity,
and its prevalence is increasing with the aging of the population. It is
estimated that between 25 percent and 50 percent of patients experience "off
episodes" in which they have impaired movement or speaking capabilities. Current
medications only control the disease's symptoms, and most drugs become less
effective over time as the disease progresses.
Cynapsus' lead drug candidate, APL-130277, is an easy-to-administer, fast-acting
and oral reformulation of an approved drug, apomorphine, used to rescue patients
from off episodes. Cynapsus is focused on rapidly maximizing the value of APL-
130277 by completing pivotal studies in advance of a New Drug Application
expected to be submitted in 2013 or 2014. Cynapsus anticipates out-licensing to
an appropriate pharmaceutical partner before such an application is submitted.
More information about Cynapsus (CTH: TSX-V) is available at www.cynapsus.ca and
at the System for Electronic Document Analysis and Retrieval (SEDAR) at
www.sedar.com.
Contact Information
Anthony Giovinazzo
President & CEO
W: (416) 703 2449 (Ext. 225)
ajg(at)cynapsus.ca
Andrew Williams
COO & CFO
W: (416) 703-2449 (Ext. 253)
awilliams(at)cynapsus.ca
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originality of the information contained therein.
Source: Cynapsus Therapeutics Inc. via Thomson Reuters ONE
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