businesspress24.com - ABLYNX ANNOUNCES 2009 FULL YEAR RESULTS
 

ABLYNX ANNOUNCES 2009 FULL YEAR RESULTS

ID: 1010738

(Thomson Reuters ONE) -


GHENT, Belgium, 25( )February 2010 - Ablynx [Euronext Brussels: ABLX] announced
today its consolidated results for 2009, which have been prepared in accordance
with IFRS as adopted by the European Union.

2009 Highlights

* ?92.3 million in cash, cash equivalents and available-for-sale financial
assets and other short term investments at year end
* ?21.3 million net cash burn for the year
* 77% increase in revenues to ?29.7 million (2008: ?16.8 million)
* Initiated a Phase II study in September for its vWF targeting
anti-thrombotic, ALX-0081, in a head-to-head comparison with ReoPro(®) as
adjunctive treatment to standard anti-thrombotic therapy in "high risk"
patients undergoing a percutaneous coronary intervention (PCI) procedure.
Showed proof-of-concept by biomarker for ALX-0081 in December with data from
the open label extension of its Phase Ib study
* Reported positive Phase I results for its anti-vWF Nanobody product,
ALX-0681, which is being developed in patients with thrombotic
thrombocytopenic purpura (TTP)
* Received Orphan Drug Designation from both the FDA and EMEA for its vWF
Nanobody programme for the treatment of TTP
* Pfizer successfully completed Phase I trials and initiated Phase II trials
for its anti-TNFa Nanobody product in rheumatoid arthritis (RA) patients in
September, which triggered a $4 million milestone payment to Ablynx
* Initiated a Phase I study in December for its RANKL targeting Nanobody,
ALX-0141, in healthy postmenopausal women. The drug is being developed
initially for the treatment of osteoporosis
* Announced a new pre-clinical development candidate, ALX-0061, a Nanobody
 product targeting IL-6R, for the treatment of autoimmune and inflammatory
diseases
* Successfully generated functional Nanobodies against GPCRs




* Awarded a total of ?1.1 million in grants to further develop new routes of
administration for Nanobodies
* Announced important developments in the administration of Nanobody products
via pulmonary and needle-free routes together with more data on its  novel
proprietary half-life extension technology called NExpedite(®)
* Received ?9 million in milestone payments from Boehringer Ingelheim, as part
of its strategic alliance

For more information, please contact:

College Hill Life Sciences - for UK/International media enquiries:
Sue Charles, Justine Lamond, Dr John McIntyre
t:   +44 (0)20 7866 7857
e:  ablynx(at)collegehill.com

Ablynx:
Dr. Edwin Moses
Chairman and CEO
t:   +32 (0)9 262 00 07
m: +44 (0)7771 954 193 / +32 (0)473 39 50 68
e:  edwin.moses(at)ablynx.com

Eva-Lotta Allan
Chief Business Officer
t:   +32 (0)9 262 00 75
m: +32 (0)475 78 36 21 / +44 (0)7990 570 900
e:  eva-lotta.allan(at)ablynx.com

Wim Ottevaere
Chief Financial Officer
t:  +32 (0)9 262 00 11
e: wim.ottevaere(at)ablynx.com





[HUG#1388791]





Complete version of the press release: http://hugin.info/137912/R/1388791/346990.pdf





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Bereitgestellt von Benutzer: hugin
Datum: 25.02.2010 - 12:11 Uhr
Sprache: Deutsch
News-ID 1010738
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